Aspirin for Peripheral Arterial Disease
Aspirin for Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a condition characterized by narrowing
of the arteries in the legs. A buildup of fatty deposits leads to
such narrowing, which impairs normal blood flow. Men are more commonly
affected by PAD. Persons with high blood pressure, high cholesterol,
and diabetes are at an increased risk of developing PAD. Those
who smoke or are obese are also at an increased risk of developing this
condition. Intermittent claudication, a condition that commonly occurs in
persons affected by PAD, is an uncomfortable or tired feeling in the legs
during walking. This happens because there is not enough blood flowing
to the muscles.
Persons with PAD who smoke are encouraged to quit. Other conditions,
such as hypertension and diabetes, should be treated. Exercise,
such as walking several times per week, is also recommended. A healthy
diet is usually recommended. Persons with PAD may be prescribed an
antiplatelet medication, such as aspirin, aspirin plus dipyridamole
(Aggrenox), or clopidogrel (Plavix). Persons who experience claudication
may be prescribed pentoxifylline (Trental or Pentoxil) or cilostazol
(Pletal). These medications work to improve blood flow. An angioplasty,
which works to open up the arteries, may be necessary for severely
blocked arteries.