Treatments for Reflux Disease
Treatments for Reflux Disease
Gastroesophageal reflux disease (GERD) is an abnormal reflux of stomach
contents into the esophagus. Heartburn is a symptom of GERD. Chest
pain, hoarseness, and cough also may be associated. Symptoms typically
occur after meals, and may be made worse by eating a large, high-fat
meal.
Treatments for GERD are available to alleviate symptoms. Proton pump
inhibitors (PPI’s), such as omeprazole (Prilosec) and esomeprazole
(Nexium), work to relieve symptoms by suppressing gastric acid secretion.
Histamine-2 receptor antagonists (H2RA’s), such as cimetidine
(Tagamet) and ranitidine (Zantac), also suppress gastric acid secretion
by blocking histamine-2 receptors on gastric cells. These medications are
available both over-the-counter and with a prescription. Antacids, such
as magnesium hydroxide (milk of magnesia) and aluminum hydroxide
(Amphogel), work to neutralize gastric acid and to increase the alkalinity
of the stomach. Gaviscon (alginic acid/aluminum hydroxide/magnesium
hydroxide) contains antacids and an absorbent that protects the esophagus
from gastric reflux. Certain nondrug changes in lifestyle can also be
useful in alleviating symptoms, including elevating the head of the bed,
reducing fat intake, eating smaller meals, and quitting smoking.